Michael C Dyle Selected Research

Muscle Denervation

1/2015	Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.
10/2013	Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.
8/2012	Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy.

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Michael C Dyle Research Topics

Disease

9	Atrophy 05/2017 - 08/2012
6	Muscular Atrophy (Muscle Atrophy) 05/2017 - 08/2012
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2023 - 01/2020
2	Obesity 01/2019 - 01/2012
1	Facioscapulohumeral Muscular Dystrophy 01/2023
1	Aneurysm (Aneurysms) 01/2020
1	Thinness 01/2019
1	Insulin Resistance 01/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Muscle Weakness 10/2015
1	Hypertrophy 05/2014
1	Fatty Liver 01/2012
1	Glucose Intolerance 01/2012

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2023 - 08/2012
4	Activating Transcription Factor 4IBA 05/2017 - 08/2012
4	Messenger RNA (mRNA)IBA 05/2015 - 08/2012
3	tomatidineIBA 10/2015 - 05/2014
3	Ursolic AcidIBA 10/2015 - 01/2012
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 08/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2012
2	Polyamine OxidaseIBA 05/2017 - 01/2015
2	Protein Kinases (Protein Kinase)IBA 05/2017 - 01/2016
2	EnzymesIBA 05/2017 - 01/2015
2	MyogeninIBA 01/2015 - 10/2013
1	Angiotensin IIIBA 01/2020
1	Fibrillin-1IBA 01/2020
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2020
1	Nonsense Codon (Nonsense Mutation)IBA 01/2020
1	FibrillinsIBA 01/2020
1	Pyruvic Acid (Pyruvate)IBA 01/2019
1	Basic-Leucine Zipper Transcription FactorsIBA 05/2017
1	MAP Kinase Kinase Kinase 4IBA 01/2016
1	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 01/2016
1	Mechanistic Target of Rapamycin Complex 1IBA 05/2014
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 10/2013
1	CaspasesIBA 08/2012

Therapy/Procedure

3	Muscle Denervation 01/2015 - 08/2012
2	Denervation 01/2015 - 10/2013
1	Therapeutics 05/2014